Ghana’s starting lineup in the Nicaragua friendly will not feature captain Andre Ayew and brother Jordan Ayew.
Black Stars gaffer Otto Addo will offer starts to the new lads in the team who could not feature against Brazil on Friday.
Andre Ayew was substituted for Antoine Semenyo while Jordan played the entire 90 minutes of the 3-0 defeat to the Selecao.
Ghana skipper Ayew played in midfield last Friday.
And to replace him, Otto Addo can trust Daniel Kofi Kyereh or Elisha Owusu to fill in the spot.
In attack against the Brazilians, Jordan was placed on the left wing.
And the Stars technical team has Osman Bukari and could field Hearts of Oak star Daniel Afriyie as well.
Kamaldeen Sulemana who started against Brazil is expected to warm the sidelines.
Ghana faces Nicaragua at 18:00 GMT Tuesday.